Efficacy Assay of Antimicrobial Agents
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In vitro Efficacy Assay of Antibacterial Agents
· Performing assay according to CLSI guidelines
· Measuring MIC50 and MIC90 for approximately
30 standard strains and 1,000-2,000 clinical isolates
· Conducting Minimum Bactericidal Concentration(MBC)
assay and Time-Kill studies to assess microbial growth
inhibition over time
· Maintaining a collection of over 1,000
antibiotic-resistant strains -
In vivo Efficacy Assay of Antibacterial Agents
· Assay the efficacy of antimicrobial agents in various
infection models of experimental animals
(mice, rats, hamsters)
· Performing efficacy assay in systemic infection, respiratory
infection, urinary tract infection, thigh infection,
skin infection, ulcerative colitis, and C. difficile infection
model(CDI)
· Conducting world-class tailored efficacy assay of
antimicrobial agents -
Resistance-Related Assay of Antibacterial Agents
· Conducting resistance frequency assay and studying
mechanisms such as cross-resistance