Efficacy Assay of Antimicrobial Agents

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Efficacy Assay of Antimicrobial Agents

Efficacy Assay of Antimicrobial Agents

Efficacy Assay of Antimicrobial Agents

  • In vitro Efficacy Assay of Antibacterial Agents

    · Performing assay according to CLSI guidelines

    · Measuring MIC50 and MIC90 for approximately
      30 standard strains and 1,000-2,000 clinical isolates

    · Conducting Minimum Bactericidal Concentration(MBC)
      assay and Time-Kill studies to assess microbial growth
      inhibition over time

    · Maintaining a collection of over 1,000
      antibiotic-resistant strains

  • In vivo Efficacy Assay of Antibacterial Agents

    · Assay the efficacy of antimicrobial agents in various
      infection models of experimental animals
      (mice, rats, hamsters)

    · Performing efficacy assay in systemic infection, respiratory
      infection, urinary tract infection, thigh infection,
      skin infection, ulcerative colitis, and C. difficile infection
      model(CDI)

    · Conducting world-class tailored efficacy assay of
      antimicrobial agents

  • Resistance-Related Assay of Antibacterial Agents

    · Conducting resistance frequency assay and studying
      mechanisms such as cross-resistance


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